B Cells in Atherosclerosis
نویسندگان
چکیده
منابع مشابه
B cells and humoral immunity in atherosclerosis.
Insights into the important contribution of inflammation and immune functions in the development and progression of atherosclerosis have greatly improved our understanding of this disease. Although the role of T cells has been extensively studied for decades, only recently has the role of B cells gained more attention. Recent studies have identified differential effects of different B-cell subs...
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Volume 3 • Issue 8 • 1000174 Pharmaceut Anal Acta ISSN: 2153-2435 PAA, an open access journal B cells play a crucial role in both humoral and adaptive immune responses and are detectable in murine and human atherosclerotic arteries. Recent findings from mouse models are starting to re-define the complex role(s) of B-cells in the atherosclerosis. We will discuss the involvement of different B-ce...
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L ymphocytes and plasma cells have long been detected in the plaque and adventitia of atherosclerotic human arteries, 1 yet their role in regulating atherosclerosis has only recently begun to emerge. 2–6 Two important studies published in 2002 provide evidence for an atheroprotective role for B cells. 3,4 More recently, 2 groups broadened our understanding of B cells and atherosclerosis by prov...
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متن کاملB Cell Subsets in Atherosclerosis
Atherosclerosis, the underlying cause of heart attacks and strokes, is a chronic inflammatory disease of the artery wall. Immune cells, including lymphocytes modulate atherosclerotic lesion development through interconnected mechanisms. Elegant studies over the past decades have begun to unravel a role for B cells in atherosclerosis. Recent findings provide evidence that B cell effects on ather...
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ژورنال
عنوان ژورنال: JACC: Basic to Translational Science
سال: 2021
ISSN: 2452-302X
DOI: 10.1016/j.jacbts.2021.01.006